A mutation within a gene can cause the premature stop codon in mRNA, which will disrupt protein production and cause cells to die. In this blog post, we’ll explore mutations in genes and how they affect protein production. We’ll also discuss the consequences of these mutations on humans.
There are two types of stop codons that affect how quickly or slowly proteins get produced:
Nonsense mutations and
Nonsense mutations occur when there is an extra, non-sense amino acid at the end of the protein sequence. If this occurs near the beginning of a protein sequence, it may not make much difference because most reading frames have several start sites–but if it’s towards the end, there might be enough change for some reading frames to misread into different sequences entirely (which would result in improper folding).
Missense mutations happen when one letter changes from A(n)GCCT…